Search JRPMS

JRPMS Vol 6, No 4, December 2022, p.121-127

doi: 10.22540/JRPMS-06-121


Review Article

Trabecular bone score for the evaluation of fracture risk: A literature review

Eleftherios-Theodoros Kaloudis

  • Postgraduate program “Metabolic Bone Diseases”, National and Kapodistrian University of Athens, Medical School, Athens, Greece

Keywords: Bone Mineral Density, Bone Strength, Fracture risk, Osteoporosis, Trabecular Bone Score


Osteoporosis is a chronic disease which constitutes a major social and economic problem, increasing the burden of health’s cost worldwide. Despite the fact that the diagnosis of osteoporosis relies on Dual energy X-ray absorptiometry (DXA), important parameters of bone strength include microarchitecture of the trabecular and cortical bone. Trabecular bone score (TBS), is a novel DXA-based technique that incorporates microarchitecture in the fracture risk assessment. In our review, we assessed the current bibliography and found numerous published articles stressing the validity of this technique for the estimation of fracture risk. As shown, TBS can be used to evaluate the risk of osteoporotic fracture in postmenopausal women and men over 50 years of age, with data for men being less extensive, as well as for the management of patients with a wide range of secondary causes of osteoporosis, including diabetes mellitus, rheumatoid arthritis, use of glucocorticoids for a long period etc.