Review Article

The role of CT and MRI in imaging of Paget bone disease

Spyridon G. Adamopoulos, Glykeria M. Petrocheilou

• Radiology Department, General State Hospital of Athens "G. Gennimatas", Athens, Greece

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Keywords: Paget, Bone, Computed tomography, Magnetic resonance imaging

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Abstract

Paget disease (PD) is a common bone disease characterized by abnormal bone turnover that follows a disorderly osteoclastic overactivity. In typical PD, imaging assessment is accomplished with conventional radiography and bone scintigraphy. CT and MRI may have complementary roles in the imaging workflow of PD preventing inappropriate investigation and helping the management planning at an early stage. Apart from discovering incidental findings, CT and MRI contribute substantially to the diagnosis of less typical cases, the delineation of PD pathology in complex anatomic areas, the differential diagnosis from sinister causes and the accurate assessment of specific complications.

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