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Volume 2, Issue 3, September 2018

Case Report JRPMS, Vol 2, No 3, September 2018, p.75-80
A new COL1A1 mutation in a Greek patient with osteogenesis imperfecta: Response to a low-dose protocol of zoledronic acid and two-year follow-up
Michail Sarantis, Panagoula Kollia, Stavroula Samara, Helen Athanasopoulou, Yolanda Gyftodimou, Dimitra Lianou, Evdoxia Mpourazani, Artemis Doulgeraki
Keywords: Osteogenesis imperfecta, Collagen, Zoledronic acid, Mutation
Abstract
Osteogenesis Imperfecta is a severe metabolic bone disorder, mainly caused by mutations of COL1A1 and COL1A2 genes that encode type I procollagen. We report a case of a 7-year-old boy with OI phenotype (recurrent, low-energy fractures, blue sclerae), whose DNA analysis revealed a new mutation of the COL1A1 gene. Herein, his two-year follow-up and his response to current treatment is described (low-dose protocol of zoledronic acid). Also, an insight is given on his metabolic bone profile, unfolding the biochemical response of bone turnover to this bisphosphonate.
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Mini Review JRPMS, Vol 2, No 3, September 2018, p.81-84
Pin site infections in pediatric population, microbiology, treatment and long-term functional disability
Sophia A. Syngouna, Pantelis K. Mitsikostas, Emmanouil Fandridis, Ioannis K. Triantafyllopoulos
Keywords: Pediatric, Hand, Upper extremity, Infections, Osteomyelitis
Abstract
Pin site or pin track infection (PTI) is the most common complication when applying external fixation. In case of failure of proper treatment, PTI will progress to soft tissue infection and osteomyelitis and cause mechanical loosening of the osteosynthesis and instability. Thus pin site infection remains a clinical challenge in deformity corrections, limb lengthening, and pediatric fracture osteosynthesis. This article discusses the pathophysiology, microbiology, and epidemiology of pin site infection in pediatric populations, as well as treatment and long-term functional outcomes.
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Review Article JRPMS, Vol 2, No 3, September 2018, p.85-88
Radiofrequency kyphoplasty for the treatment of osteoporotic vertebral fractures: A review of the literature
Stylianos S. Pernientakis, Panagiotis T. Masouros, Christos P. Margiannis, Aristomenis Vasilopoulos
Keywords: RF Kyphoplasty, Radiofrequency kyphoplasty, Osteoportic vertebral fractures, Balloon kyphoplasty
Abstract
Vertebral fractures are a leading cause of disability among the elderly people. While conservative treatment remains the mainstay of treatment, other techniques such as kyphoplasty are reserved for cases of lasting pain. However, cement extravasation has traditionally been a relatively common complication of all vertebra augmentation procedures. Radiofrequency kyphoplasty (RF-VTA) is a relatively new method, which relies on the targeted creation of minimally destructive paths, thus preserving the microarchitecture of the trabeculae. In addition, it yields comparable or superior outcomes than compatible techniques. The aim of this project is to review all the studies concerning this novel technique and provide the reader with its results and potential adverse effects.
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Original Article JRPMS, Vol 2, No 3, September 2018, p.89-94
Meniscal repair using fibrin clot from autologous blood: description of the surgical technique
Chrysanthos Chrysanthou, Nikolaos Laliotis, Nikiforos Galanis, George Paraskevas, Michael Potoupnis, Fares Sayegh, George Kapetanos
Keywords: Meniscus, Meniscus repair, Biological augmentation techniques, Surgical technique, Fibrin clot
Abstract
The crucial role of the menisci in function and biomechanics of the knee has been increasingly recognized and well described during the past several years. Meniscectomy was a gold standard treatment for a torn meniscus. Reviewing the literature, shows that this procedure is deleterious for the chondral surface. In the last decades, orthopaedic surgeons give a battle to salvaging and repair a torn meniscus, when this is possible. Clinical studies have shown that the introduction of biological augmentation techniques has the potential to enhance meniscus repair especially in young active individuals. Fibrin clot is relative quick to reproduce and easy to use technique which promises encouraging results in repairing the torn meniscus and in the same time is considered one of the most cost effective solutions comparing with others. In this paper our aim is to present the surgical technique of preparation and use of the fibrin clot form autologous blood step-by-step in case series of 24 patients. However, despite the relative ease preparation of fibrin clot from autologous blood, the placement and stabilizing it into the gap of the meniscal rupture arthroscopically is challenging.
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